Table 4.
Effects of nerve growth factor on cold responsiveness and the cold-activated current
| NGF | n | noNGF | n | P* | |
|---|---|---|---|---|---|
| ΔFIF0 on colling | 0.40 ± 0.16 | 205 | 0.33 ± 0.16 | 50 | 0.007 |
| Threshold temperature for increase in [Ca2+] | 30.5 ± 3.8 | 205 | 27.9 ± 3.5 | 50 | <0.001 |
| Threshold temperature for increase in [Ca2+] in 100 μm (-) menthol (°C) | 35.4 ± 4.0 | 26 | 29.9 ± 8.0 | 12 | 0.008 |
| Cold-induced depolarisation at 18°C(mV) | 28.9 ± 8.1 | 45 | 20.4 ± 8.3 | 16 | <0.001 |
| Depolarisation threshold (°C) | 31.9 ± 8.1 | 46 | 28.3 ± 3.8 | 13 | 0.04 |
| Cold-actived current at 18 ° (pA) | 137 ± 90 | 63 | 60 ± 52 | 15 | 0.002 |
| Cold-activated current threshold (°C) | 31.5 ± 2.7 | 62 | 28.6 ± 2.9 | 13 | <0.001 |
*
student's unpaired t test.