Skip to main content
. 2002 Oct 18;545(Pt 2):485–499. doi: 10.1113/jphysiol.2002.031161

Table 1.

Conductivity of the intact epithelium and decrease of gleakbetween 2 and 8 min post lesion

Control Cytochalasin D Butanedione monoxime Low free[Ca2 +]o ML-7 Y-27632
Gintact (mS cm−2) 1.38 ± 0.07 15.92 ± 4.55 *** 3.02 ± 0.39*** 15.27 ± 2.74 *** 1.66 ± 0.14n.s. 1.40 ± 0.09 n.s.
(gleak,2min gleak,8min)/gleak,2min 61 ± 3% 3 ± 2%*** 31 ± 3%*** 74 ± 5%n.s. 14 ± 3%*** 66 ± 4%n.s.
n (m) 24(23) 7(5) 10(6) 7(5) 8(8) 8(7)

Conductivity of intact epithelium, Gintac, apart from apoptosis or edge damage, was measured in the conductance scanning set-up before inflicting a lesion. The decrease in gleak, associated with a single-cell lesion, between 2 and 8 min post lesion was determined. n, number of leaks; m, number of monolayers. Wilcoxon-Mann-Whitney U test with Bonferroni's correction for multiple testing

n.s.

P > 0.05

***

P < 0.002.