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. 2002 Nov 1;545(Pt 3):751–766. doi: 10.1113/jphysiol.2002.028381

Figure 11. Effects of low pHo on the KCNE1 deletion mutant Δ11-38 co-expressed with WT KCNQ1 in Xenopus oocytes.

Figure 11

A, representative current traces recorded at pH 7.4 (left) and pH 5.5 (right) using the activation protocol described in Fig. 2A. B, current-voltage relationship of IKs current recorded at pH 7.4 (open squares) and pH 5.5 (filled squares) (n = 6). C, the normalized conductance (G/Gmax) of the tail currents is plotted as a function of the membrane voltage (mV) at pH 7.4 (open squares) and pH 5.5 (filled squares; n = 6). D, τdeact data were obtained at pH 7.4 and 5.5 from the monoexponential fit of the tail currents measured at -60 mV from a prepulse potential of +30 mV (n = 6; *P < 0.01).