Table 1.

Effect of BayK8644 on endothelial and vascular smooth muscle cell membrane potential (mV) in the absence and presence of 18βGA

Control	Endothelium -37±0.9* (n = 38)			Vascular smooth muscle -49.1±1.1 (n = 38)
	Before	After	Δ	Before	After	Δ
BayK8644 (n = 14,14)	−37.4 ± 1.5	−27.0 ± 2.0†	+10.4 ± 1.2	−49.9 ± 2.2	−37.0 ± 2.6†	+12.9 ± 1.5
18βGA (n = 38,38)	−37.8 ± 0.9	−32.7 ± 0.7‡	+4.1 ± 1.1	−49.1 ± 1.1	−48.8 ± 1.0	+0.3 ± 1.0
18βGA + BayK8644 (n = 38,38)	−32.3 ± 1.0	−29.0 ± 1.2	+3.3 ± 0.9§	−49.0 ± 1.7	−34.8 ± 2.0‡	+14.2 ± 1.4

^*Significantly different from smooth muscle cell membrane potential (P < 0.01).

^†Significantly different from value before Bay K8644 (P < 0.01).

^‡Significantly different from value before 18βGA (endothelium) or 18βGA + BayK8644 (vascular smooth muscle; P < 0.011).

^§Significantly different from value in BayK8644 but absence of 18βGA (P < 0.01).