Figure 4. Effect of inhibitors of adenylate cyclase, protein kinase A and protein kinase C on the [Ca²⁺]_i decrease induced by dexamethasone in 16HBE14o- cell monolayers.

Effect of (A) 500 μm MDL 12, 230 hydrochloride, an inhibitor of adenylate cyclase, (B) 200 μm Rp-adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt (Rp-cAMP), an inhibitor of protein kinase A, (C) 1 μm thapsigargin (thapsi), a Ca²⁺-ATPase pump inhibitor, and (D) 0.1 μm chelerythrine chloride, an inhibitor of protein kinase C, on the [Ca²⁺]_i decrease induced by dexamethasone (1 nm) in 16HBE14o- cell monolayers.