Figure 2. Ipsi-lesional flocculectomy does not prevent adaptive changes in the functional efficacy of GABA receptors in MVN neurons during compensation.

A, firing rate histograms showing the dose-dependent inhibition of the spontaneous discharge of two MVN neurons by bath-application of muscimol (upper panel) and baclofen (lower panel). The bars above the data indicate the 60 s period of application of the agonists. The inhibitory response was measured as the maximal inhibition of firing rate expressed as a percentage of the resting discharge rate for each cell. B, dose-response relationships for the inhibitory response to muscimol (left panel) and baclofen (right panel), of MVN neurons in control slices (○) and in slices prepared from animals that underwent iFX+UL 4 h earlier (•). Data are means and s.e.m.