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. 2002 Oct 25;545(Pt 3):783–805. doi: 10.1113/jphysiol.2002.029249

Figure 10. Computer simulation showing that resonance at depolarized and hyperpolarized membrane potential is due to different mechanisms.

Figure 10

A1, voltage responses (upper trace) to ZAP current (lower trace) from the model cell at -58 mV, before and after removal of IM, Ihor INaP. Resonance at depolarized level was fully blocked by removal of IM, but was resistant to removal of Ih. Removal of INaP reduced the peak-to-peak amplitude of the resonance, but caused little change of resonance frequency at -58 mV. B1, voltage response (upper trace) to ZAP current (lower trace) from the model cell at -78 mV, before and after removal of IM, Ih or INaP. Resonance at -78 mV was resistant to removal of INaP and IM, but was blocked by removing Ih. A2 and B2, impedance magnitude plotted as a function of input frequency, from the traces in A1 and B1, respectively.