Table 1.
Model parameters of INaP, Ih and IM
INaP | Ih | Im | |
---|---|---|---|
General parameters | |||
Erev | 30 | −17 | −80 |
Number of particles | 1 | 1 | 2 |
Particle parameters* | |||
z(valence) | 5 | −5 | 15 |
γ | 0.5 | 1 | 0.45 |
Base rate (1/ms) | 1 | 1 | 0.003 |
V1/2(mV) | −49 | −95 | −57.5 |
τ0(ms) | 1 | 150 | 0.0043 |
‘Extended Hodgkin-Huxley’ description.
Simulation temperature: 31°C. V½ gives the midpoint of the activation curve; z is the valence, setting the steepness of the activation curve; γ is the symmetry parameter determining the skew of τ(v); the base rate (K) is the leading coefficient of α(V) and β(V);τo represents a ratelimiting step in the state transition.