Table 2.
Biological activity of conorfamide-Sr2
| Organism | Dose (pmol) | Effect |
|---|---|---|
| Mouse | 250 | Brief clonus of limbsa; mild hyperactivityb |
| 1000 | Long clonusc of limbs; strong hyperactivityd | |
| Pomacea paludosa (freshwater snail) | 250 | Hyperactivitye |
| Patella opea (limpet) | 50 | Mild paralysisf |
| 250 | Strong paralysisg | |
| Lebistes reticulates (freshwater fish) | 50, 250 | No effect |
a
~ 10 s.
b
Continuous wandering.
c
~ 1 min.
d
Continuous wandering and jumping.
e
Continuous displacement around the aquarium.
f
Partial loss of attachment to the Petri dish; no reaction after being touched.
g
Complete stillness; loss of attachment to the Petri dish; no reaction after being touched.