Table 4.

Multivariate-adjusted ORs and 95% CIs in subjects with severe ED (IIEF ≤ 7) compared with those with normal erectile function.

	Model I OR (95% CI)	Model II OR (95% CI)	Model III OR (95% CI)	Model IV OR (95% CI)
Age (years)
< 60	1.0	1.0	1.0	1.0
60–70	4.9 (1.0–24.0)*	4.5 (1.0–20.6)*	4.3 (0.9–20.7)	4.8 (0.9–25.4)
≥ 70	35.9 (6.5–197.5)#	27.1 (5.4–134.8)#	22.1 (4.3–114.4)#	30.9 (5.2–182.1)#
	p for trend: < 0.001	p for trend: < 0.001	p for trend: < 0.001	p for trend: < 0.001
Testosterone < 11 (nmol/L)		2.4 (0.7–7.8)
Free testosterone < 0.23 (nmol/L)			4.9 (1.3–18.9)**	4.7 (1.2–18.9)**
Arsenic exposure (ppb)
≤ 50	1.0			1.0
> 50	7.7 (2.0–30.0)#			7.5 (1.8–30.9)**
Cigarette smoking	1.2 (0.4–3.0)	1.4 (0.6–3.7)	1.4 (0.5–3.5)	1.2 (0.4–3.2)
Diabetes mellitus	5.9 (1.3–27.22)**	3.8 (1.0–15.2)	3.7 (0.9–14.5)	5.5 (1.2–24.2)**
Hypertension	0.5 (0.2–1.5)	0.4 (0.1–1.1)	0.4 (0.1–1.2)	0.4 (0.1–1.4)
Cardiovascular disease	6.5 (1.3–32.1)**	4.4 (1.0–19.4)*	4.2 (0.9–19.3)	5.3 (1.0–26.8)**

Models show relationship between severe ED and arsenic exposure (model I), severe ED and testosterone (model II), severe ED and free testosterone (model III), and severe ED and arsenic exposure, adjusting for free testosterone (model IV).

^*p = 0.05.

^**p < 0.05.

^#p < 0.005.