Fig. 6.
Model structure-activity screen of ten pyridopyrimidine compounds and controls. The kinase assay was performed with K562 lysates using the standard assay conditions with varying concentrations of each inhibitor (1 to 1000 nM).
Model structure-activity screen of ten pyridopyrimidine compounds and controls. The kinase assay was performed with K562 lysates using the standard assay conditions with varying concentrations of each inhibitor (1 to 1000 nM).