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Functional consequences of the binding between S18-2 and EBNA-6: S18-2 bound to EBNA-6 translocates to the nucleus. This may facilitate the binding of S18-2 to pRb. As long as it is bound to S18-2, pRb may not influence the level of free E2F1. This may promote the entry of the EBV infected B cell into the cell cycle.
