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. 2008 Apr 7;105(14):5337–5342. doi: 10.1073/pnas.0710981105

Fig. 4.

Fig. 4.

General binding mode of MFA-1. (A) Final refined 2Fo−Fc electron density for MFA-1 contoured at 1.5 σ. (B) Results of the superposition of FXR molecules from the MFA-1(yellow) structure with rat FXR in complex with 6-ethyl-CDCA (magenta, PDB ID code 1OSV). The cα rmsd for the superposition is 1.177 Å. (C) Results of the superposition of FXR molecules from the MFA-1(yellow) structure with human ERβ in complex with estradiol (blue, PDB ID code 1QKT). The cα rmsd for the superposition is 4.217 Å.