Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Specific interactions between MFA-1 and FXR. (A) Interactions with the steroid ring system of MFA-1 (yellow). Side chains discussed in the text are colored cyan and labeled. (B) Stabilization of the helix 1–2 linker by MFA-1. Residues discussed in the text are labeled. (C) Stabilization of helix 12 by interactions with the hydroxy benzoyl group. Residues discussed in the text are colored cyan and labeled. Helix 3 is depicted as a thin trace for clarity.
