Fig. 6.

SKF 105,111 induces increased contextual freezing behaviors and reduces hippocampal Allo content in group-housed male mice. Total duration of contextual freezing time was measured 24 h after the contextual training session. SKF 105,111 was injected 4 h before the training fear-conditioning session or before measurements of Allo content in the hippocampus (Hip). Each value is the mean ± SEM of five animals. *, P < 0.05 or †, P < 0.01 in SKF 105,111-treated groups compared with the respective vehicle-treated group (one-way ANOVA, followed by Bonferroni test).