Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CYP2C19 genotype frequencies and metabolic ratio of omeprazole in 265 healthy Japanese volunteers
| Genotype | Number (% of total) | Metabolic ratio (95% CI interval) | |
|---|---|---|---|
| EM (n = 217) | *1/*1 | 94 | 2.18 ± 2.24 |
| (35.5) | (1.71, 2.65) | ||
| *1/*17 | 3 | 0.87 ± 0.25 | |
| (1.1) | (0.24, 1.49) | ||
| *1/*2 or *1/*3 | 116 | 3.97 ± 3.15 | |
| (43.8) | (3.38, 4.55) | ||
| *17/*2 or *17/*3 | 4 | 3.85 ± 2.70 | |
| (1.5) | (−0.45, 8.15) | ||
| PM (n = 48) | *2/*2, *2/*3 or | 48 | 32.32 ± 14.55 |
| *3/*3 | (18.8) | (28.00, 36.64) |
EM, extensive metabolizer; PM, poor metabolizer.
