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. 2007 Oct 24;65(3):338–346. doi: 10.1111/j.1365-2125.2007.03031.x

Table 4.

Ratio of geometric mean pharmacokinetic parameters and 90% confidence intervals (anova) based on age, gender, and BMI

	Ratio
Pharmacokinetic parameter	Age (Elderly vs. young)	Gender (Male vs. female)	BMI (≤25 kg m⁻²vs.≥29 kg m⁻²)
Vildagliptin
C_max	1.17 (1.02, 1.35)	0.90 (0.78, 1.04)	0.96 (0.83, 1.11)
AUC(0,t)	1.31 (1.18, 1.45)	0.93 (0.84, 1.03)	0.90 (0.81, 0.99)
AUC(0, ∞)	1.31 (1.18, 1.45)	0.93 (0.84, 1.03)	0.90 (0.81, 0.99)
LAY151
C_max	1.61 (1.41, 1.84)	0.87 (0.76, 1.00)	0.99 (0.86, 1.13)
AUC(0,t)	1.70 (1.51, 1.92)	0.93 (0.82, 1.05)	0.98 (0.86, 1.11)
AUC(0, ∞)	1.77 (1.56, 2.02)	0.97 (0.85, 1.10)	0.95 (0.83, 1.08)