Table 2.
Demographics of study patients
| Characteristic | All patients included | Patients with no ADRs | All patients with ADRs | Patients with ADRs on admission | Patients with ADRs during hospital stay |
|---|---|---|---|---|---|
| Number of patients | 665 | 572 | 93 | 55 | 41† |
| Age in years (median and IQR) | 42 (30–60) | 42 (30–60) | 42 (33–66) | 53 (35–73) | 38 (28–49) |
| Female (%) | 340 (51.1) | 288 (50.3) | 52 (55.9) | 32 (58.2) | 21 (51.2) |
| Median length of stay in hospital | 6 (4–10) | 6 (4–9) | 10 (6–15.5)* | 8 (5–12) | 14 (10.5–19) |
| HIV status (% of total) | |||||
| Positive | 216 (32.5) | 177 (30.9) | 39 (41.9)* | 21 (38.2) | 19 (46.3) |
| •on ART | 35 (5.3) | 20 (3.5) | 15 (16.1)* | 14 (25.5) | 2 (4.9) |
| •not on ART | 181 (27.2) | 157 (27.4) | 24 (25.8) | 7 (12.7) | 17 (41.5) |
| Negative | 52 (7.8) | 46 (8.0) | 6 (6.5) | 2 (3.6) | 4 (9.8) |
| HIV status unknown | 397 (59.7) | 349 (61.0) | 48 (51.6) | 32 (58.2) | 18 (43.9) |
| Deaths during hospitalization (regardless of cause) (%) | 80 (12.0) | 68 (11.9) 0 (0) | 12 (12.9) | 7 (12.7) | 8 (19.5) |
*
P < 0.05 when comparing patients with adverse drug reactions (ADRs) and patients with no ADRs.
†
Includes three patients who were admitted with an ADR and also developed an ADR during hospital stay. ART, Antiretroviral therapy; IQR, interquartile range.