Table 3.
Haematological and biochemical parameters of Hdahmp and its complexes.
| Parameters | ||||||
|---|---|---|---|---|---|---|
| Compound | Hb(1) (12–16 g/dl) | RBCs(2) (4.0–6.0 × 106 cell/cm3) | HCT(3) (35.0–50.0%) | WBCs(4) (4000–11000 × 106 cell/cm3) | EAC Count (× 106 cell/cm3) | MSt/day(5) |
| Hdahmp | 10.7 | 6.3 | 40.3 | 8800 | 44.8 | 13.2 |
| [Pd(bpy)(dahmp)]Cl | 11.4 | 6.4 | 40.3 | 12000 | 31.8 | 11.4 |
| [Ag(bpy)(Hdahmp)]NO3 | 11.0 | 6.3 | 41 | 9000 | 30.4 | 11.2 |
| 5-fu | 10.2 | 6.0 | 37.7 | 7600 | 80 | 13.6 |
| Control (0.9% NaCl) | 7.8 | 4.72 | 22.2 | 2400 | 220 | 9.0 |
(1)Hb = hemoglobin, (2)RBCs = red blood cells count, (3)HCT = hemato crate value, (4)WBCs = white blood cells count values in normal mice are in parentheses, (5)the mean survival time.