Table 2.

Clinical characteristics of the patient group

Patient no.	Sex	Age at first scan (years)	Age at second scan (years)	Interval between scans (years)	Rapid cycling	Medications at scan 1	Medications at scan 2	Comorbid diagnoses
1	Female	11.7	14.3	2.6	Scans 1 & 2	None	None	Social phobia
2	Female	15.8	18.6	2.8	Scan 2	None	Birth control pills	None
3	Female	16.6	18.8	2.2	Scans 1 & 2	None	Birth control pills	None
4	Female	17.2	20.2	3.0	Scan 2	Carbamazepine, levothyroxine	None	Oppositional defiant disorder, post-traumatic stress disorder, hypothyroidism
5	Female	21.5	23.6	2.1	Scan 1	None	None	History of alcohol dependence, hallucinogen and marijuana abuse
6	Male	10.7	12.7	2.0	Scans 1 & 2	Lithium	None	Oppositional defiant disorder
7	Male	11.7	14.0	2.2	Scan 2	VPA, olanzapine, methylphenidate, clonidine	Olanzapine, methylphenidate	ADHD, developmental coordination disorder
8	Male	12.0	14.6	2.5	Scan 1	VPA, nortriptyline	VPA, nortriptyline, methylphenidate	Learning disorder NOS
9	Male	12.2	15.6	3.3	None	Lithium, risperidone, sertraline	Lithium, VPA, risperidone, sertraline, atomoxetine	Learning disorder NOS
10	Male	20.8	23.0	2.2	Scans 1 & 2	None	None	None

VPA = valproic acid; ADHD = Attention-deficit hyperactivity disorder; NOS = not otherwise specified.