Table 1.

Pharmacokinetic properties of trandolapril (T) in healthy volunteers

Dosage	Duration	Cmaxa (mg/mL)	Tmaxb (hour)	AUC ng/mL (hour)	T1/2 (hour)
T 0.5 mg	Single dose	0.43 (0.1)*	1#	0.4 (0.11)*	0.71 (0.08)*
T 1 mg	Single dose	0.86 (0.1)*	0.5#	0.95 (0.15)*	0.74 (0.09)*
T 2 mg	Single dose	1.68 (0.33)*	0.5#	1.86 (0.3)*	0.68 (0.05)*
T 4 mg	Single dose	3.32 (0.56)*	0.5#	3.64* (0.44)*	0.76 (0.13)*
T 2 mg	qd for 10 days	3.19 (0.33)*	1#	3.67 (0.97)*	0.68 (0.07)*

^aC_max, peak plasma concentration.

^bT_max, time to C_max

^*Mean.

^#Median.