FIGURE 7. Model of Fbg substrate recognition by the SC-(1–325)·Pre 2 complex.
The model shown was generated by a manual docking procedure as described in the text under “Experimental Procedures.” As illustrated, the similarity of the C-terminal repeats (SCAla467-SCGly655) to those of Efb suggests their preferential binding to the α-chain of Fbg fragment D. The two Aα-chains threading through the active centers of the bound and activated Pre 2 molecules are shown in green.