Table 2.

Network of activated regions for control subjects and type 1 diabetic patients (P < 0.001)

Region	Cluster size	Talairach coordinates (27)			Direction of statistical differences between regions common to both groups
		x	y	z
Nondiabetic control subjects (n = 6)
L hypothalamus	939	0	−4	−7	DM > Cont subj
L uncus	750	−12	−4	−20	Cont subj > DM
L putamen	559	−19	19	−7	Cont subj > DM
R brainstem	81	3	−16	15	Cont subj = DM
L ACC	568	−2	8	−5	Cont subj > DM
R ACC	58	3	36	−2
L medial frontal gyrus	18	−4	60	4
R medial frontal gyrus	36	2	64	3
L posterior cingulate	237	−2	−46	15
Type 1 diabetic patients (n = 7)
L hypothalamus	985	0	−4	−7
L uncus	79	−20	−2	−26
L putamen	244	−43	−4	−6
R brainstem	74	8	−26	−15
L ACC	455	−2	8	−5
L brainstem (pons)	281	−9	−34	−30
L superior temporal gyrus	234	−46	4	−7
L insula	480	−45	4	2

Activated regions common to both groups appear in bold. ACC, Anterior cingulate cortex; Cont subj, control subjects; DM, diabetic patients; L, left; R, right.