Figure 1.
Genetic relatedness and geographic distribution of WNV genotypes (a) Maximum likelihood phylogenetic tree of 21 complete genomes of WNV. Viruses are grouped according to the four described lineages of WNV, and the substituted amino acid at each NS3-249 site is indicated (and color coded). The most parsimonious reconstruction of the amino acid residue at internal nodes is also shown. The tree is midpoint rooted, and branch lengths are drawn to scale to indicate the number of substitutions per site. For details on the strains used in this tree, including isolate name, infected organism and GenBank accession number, see Methods. The asterisks represent nodes with bootstrap support values >95%. (b) Geographic distribution of WNVs in Africa, Europe and Asia (light blue). Colored dots indicate NS3-249 genotypic identity.