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. Author manuscript; available in PMC: 2008 Apr 10.
Published in final edited form as: J Immunol. 2003 May 1;170(9):4818–4825. doi: 10.4049/jimmunol.170.9.4818

FIGURE 3.

FIGURE 3

Treatment of NZM.2410 mice with anti-IL-4 mAb (11B11) inhibits IL-4 production, and reduces IgG1 and IgE levels. Twenty-week-old female NZM.2410 mice were treated with 11B11, GL113 (control Ig), or PBS. A, IL-4 and IFN-γ levels in supernatants of spleen cells cultured with Con A for 48–72 h. B and C, Total serum IgG1, IgG2a, and IgE levels were determined in 28- to 30-wk-old mice (p < 0.05–0.01 in 11B11-treated vs control groups; n = 5–8 mice per group). Results are expressed as the mean ± SE values from a representative of two independent experiments.