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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Ann Biomed Eng. 2008 Feb 14;36(5):821–830. doi: 10.1007/s10439-008-9444-9

FIGURE 7.

FIGURE 7

Gamma camera imaging of in vivo scFv biodistribution at 10 days post-injection. Mice were imaged on a gamma camera imaging system at 24 h post-injection and every 24 h after for up to 10 days (or approximately 3 half-lives for the 111In). Mouse on the left side has left hind limb tumor treated with 6 Gy radiation, and right hind limb tumor treated with TNFα (positive control). Mouse on the right side has left and right hind limb tumors treated with sham radiation dose of 0 Gy (as negative control). Specific targeting was seen with scFv 10Acys to the tumor treated with 6 Gy and the tumor treated with TNFα as compared to untreated control tumors.