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. 2008 Feb 28;4:8. doi: 10.1186/1744-8069-4-8

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Copyright © 2008 Yang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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met-Enkephalin immunohistochemical staining in spinal cord (T9–10). A. The spinal cord from a naïve rat is shown for comparison to (B) the spinal cord of animals with diet-induced pancreatitis at week 10. C. The expression of met-ENK after application of vehicle or HSV-β-gal is similar to naïve rats (A). D. Met-ENK expression was significantly increased in HSV-ENK vector-treated animals compared to controls. Met-ENK in the dorsal horn (laminae I–II) of the thoracic spinal cord was increased bilaterally.