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. 2008 Feb 27;5:8. doi: 10.1186/1742-2094-5-8

Table 3.

Cytokine and chemokine protein levels (pg/mg) ± SEM in substantia nigra of animals treated with IL-1ra or vehicle. All animals received an intra-nigra injection of LPS 9 days prior to drug treatment. IL-1ra treatment lasted for 3 days.

Cytokine/Chemokine Vehicle IL-1ra
IL-1β 9.32 ± 1.38 9.61 ± 2.48
MCP-1 12.48 ± 2.58 10.56 ± 1.71
IFN-γ 2.42 ± 0.38 1.32 ± 0.23*
IL-10 0.22 ± 0.03 0.15 ± 0.02
IL-1α 1.27 ± 0.04 1.03 ± 0.17
TNF-α 2.35 ± 0.29 1.16 ± 0.22*
Fractalkine 14.64 ± 1.37 15.21 ± 1.45
IL-6 13.18 ± 2.71 9.13 ± 1.25

*p < 0.05; IL-4 was below detectable limits.