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. 2008 Apr 14;205(4):897–913. doi: 10.1084/jem.20071046

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Copyright © 2008, The Rockefeller University Press

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Figure 4. — Overexpression of IL-9 in the intestine induces features of an intestinal anaphylaxis genotype. (A) Quantitative PCR analysis of mast cell gene mRNA expression in the jejunum of iFABPp-IL-9Tg and BALB/c WT. Results are expressed as the gene/GADPH ratio in respect to fold change over BALB/c WT. Gene expression was normalized to GADPH expression in each individual sample. Circles represent individual mice and black line represents mean value in each group (B) Genome-wide expression gene profile comparative analysis of iFABPp-IL-9Tg and BALB/c WT mice compared with OVA-sensitized, OVA-challenged BALB/c WT mice (6). Values represent fold increase over respective control. The complete dataset is available at the NCBI gene expression Omnibus (http://www.ncbi.nlm.gov) accession no. GSE10658.