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. 2008 Apr 14;205(4):897–913. doi: 10.1084/jem.20071046

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Copyright © 2008, The Rockefeller University Press

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Figure 6. — Overexpression of IL-9 in the intestine increases susceptibility to oral antigen–induced intestinal anaphylaxis. Diarrhea occurrence (A), mean number of mast cells per high power field (hpf; B), serum mouse mast cell protease-1 (C), and serum antigen-specific IgE (D) in OVA- or saline-sensitized and subsequently OVA-challenged BALB/c WT and iFABPp-IL-9Tg mice. (E) Diarrhea occurrence in OVA-challenged BALB/c WT and iFABPp-IL-9Tg mice and subsequently challenged with BSA. (A) Data represented as the percentage of diarrhea occurrence over number of OVA challenges. (B–D) Data are represented as the mean ± the SEM; 4–5 mice per group from n = 3 experiments. (E) Data are represented as the percentage of diarrhea occurrence over the number of OVA challenges, and then subsequent BSA challenge.