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. 2008 Apr 14;205(4):897–913. doi: 10.1084/jem.20071046

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Copyright © 2008, The Rockefeller University Press

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Figure 7. — Overexpression of IL-9 in the intestine increases local Th2 responses after OVA i.g. challenge. IL-4 protein levels in jejunal lysates (A) and percentage of CD4⁺ IL-4⁺ cells (B) in the lamina propria of the jejunum of BALB/c WT and iFABPp-IL-9Tg mice after i.g. OVA challenges. Antigen-specific IgG₁ (C) and total IgE protein levels (D) in jejunal lysates from BALB/c WT and iFABPp-IL-9Tg mice under basal conditions and after 5 i.g. OVA challenges. (A) Data are expressed as protein level in picograms/milliliter per milligram protein. In A, each circle represents an individual mouse, and the black line represents the mean value in each group. (A–D) Data are represented as the mean ± the SEM; 4–5 mice per group from at least n = 2 experiments. Dotted line depicts the detection limit.