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. 2008 Apr 14;205(4):981–992. doi: 10.1084/jem.20071854

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Copyright © 2008, The Rockefeller University Press

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Figure 2. — ECTV Δ166 is avirulent in immunocompetent mice but virulent in IFNAR1-deficient mice. (A) BALB/c mice were infected with 300 PFU of the indicated viruses. Virus titers in the infected footpad and spleen were determined at the indicated times. Data points are means ± SD of three mice. (B) BALB/c mice were infected with the indicated viruses, and organs were harvested and photographed 7 d PI. (C) BALB/c mice were infected in the footpad with 300 PFU of the indicated viruses and observed for survival. Data correspond to five mice per group. (D) IFNAR1-deficient or control 129S2/SvPasCrl mice were infected with 300 PFU of the indicated viruses and observed for survival. Data correspond to five mice per group.