Table 2.

Summary of p18^INK4C Gain-of-Function and Loss-of-Function Studies

				Tumorigenicity (Soft Agar Growth)
	CDKN2A	p18INK4C	CCND1/CDK4	p18INK4C Expression	p18INK4C KD
LN-18	null	WT	WT	decrease	increase
LN-444	null	WT	WT	decrease	increase
Hs683	null	WT	WT	N/A	increase
LN-229	null	null	WT	decrease	no change
U87MG	null	null	WT	decrease	N/A
LN-Z308	WT	WT	amp	no change	no change