Table 3. Local Reactions.

Reaction	Group A 4-site (n = 55)	Group B 8-site (n = 60)	Group D 2-site (n = 58)	Group E IM (n = 56)	P-value
Redness	53 (96.4%)	58 (96.7%)	54 (93.1%)	14 (25.0%)	<0.0001
Swelling	42 (76.4%)	48 (80.0%)	46 (79.3%)	8 (14.3%)	<0.0001
Hardness	41 (74.6%)	44 (73.3%)	38 (65.5%)	9 (16.1%)	<0.0001
Tenderness/ Pain	39 (70.9%)	35 (58.3%)	41 (70.7%)	31 (55.4%)	0.2
Any above reactions	53 (96.4%)	58 (96.7%)	54 (93.1%)	33 (58.9%)	<0.0001*
Itchiness	26 (47.3%)	29 (48.3%)	28 (48.3%)	2 (3.6%)	<0.0001
Lymphadenopathy	5 (9.1%)	15 (25.0%)	8 (13.8%)	0 (0%)	<0.0001

*: Post hoc test: A vs E, P<0.0001; B vs E, P<0.001; D vs E, P<0.001.