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(A and B) Switching rate kAB for the general switch as a function of the dimerization rate kf (A) and the rate of operator binding kon (B). Dissociation rates are scaled such that the equilibrium constants remain constant: 
and 
Panels C and D show the probability ρ(q*) of being at the dividing surface, as a function of kf (C) and kon (D). Panels E and F show the kinetic prefactor, as defined by Eq. 1, as a function of kf (E) and kon (F).
