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. Author manuscript; available in PMC: 2008 Apr 11.
Published in final edited form as: J Biol Chem. 2005 Apr 13;280(25):23523–23530. doi: 10.1074/jbc.M500894200

Fig. 3. Kinetic parameters for fIX cleavage by fXIa.

Fig. 3

A, initial rates of fIX hydrolysis by 0.4 nM fXIa active sites (υo) as a function of fIX concentration ([fIX]o). B, progress curves of fIXa generation ([fIXa]) from fIX at 25 (△), 50 (▲), 100 (□), 250 (■), 500 (○), and 1000 nM (●). The lines represent the least-squares fits to the data with the parameters listed in Table I. Rates were measured and analyzed as described under “Experimental Procedures.”