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. Author manuscript; available in PMC: 2008 Apr 11.
Published in final edited form as: J Biol Chem. 2005 Apr 13;280(25):23523–23530. doi: 10.1074/jbc.M500894200

Fig. 4. Inhibition of fXIa activation of fIX by aprotinin and fIXai.

Fig. 4

A and B, initial velocities of activation of fIX by 0.4 nM fXIa active sites (υo) as a function of fIX concentration ([fIX]o) in the presence of aprotinin at 0 (○), 1.2 (●), or 3.8 (□) μM (A) or factor IXai at 0 (○), 1.5 (●), and 3.0 (□) μM (B). Lines represent the least-squares fits to the data with the parameters listed in Table I. Data shown are means for two separate experiments. Rates were measured and analyzed as described under “Experimental Procedures.”