TABLE 3.

Fecal recovery of OPT-80 and its metabolite OP-1118 in the single-dose study^a

Subject	Dose (mg)	OPT-80		OP-1118		Total % of dose
		Recovery (mg)	% of dose	Recovery (mg)	% of dose
009	200	63.25	31.63	249.09	124.55	156.17
010	200	49.70	24.85	203.30	101.65	126.50
011	200	45.31	22.66	115.47	57.74	80.39
013	200	90.83	45.42	198.65	99.33	144.74
014	200	55.11	27.56	125.80	62.90	90.46
016	200	54.02	27.01	201.42	100.71	127.72
001	300	36.47	18.24	62.33	31.17	49.40
002	300	86.76	43.38	146.06	73.03	116.41
003	300	47.97	23.99	161.50	80.75	104.74
005	300	39.10	19.55	34.73	17.37	36.92
006	300	148.30	74.15	221.63	110.82	184.97
008	300	123.52	61.76	237.76	118.88	180.64
Mean (SD)			35.01 (17.72)		81.57 (34.15)	116.59 (47.05)

^aData are not presented for the 100- and 450-mg dose groups, who completed the study as outpatients.