TABLE 1.
Plasmid | Original host (year of isolation) (reference) | Size (bp) | GC content (%) | No. of genes | No. of indels in the backbone | Antibiotic resistance profilea |
---|---|---|---|---|---|---|
R388 | E. coli (1972) (22) | 33,920 | 57.5 | 43 | 1 | Tpr, Sur |
pIE321 | Salmonella enterica (1996) (35) | 38,151 | 58.4 | 46 | 2 | Tcr, Smr |
R7K | Providencia rettgeri (1972) (17) | 39,792 | 56.7 | 42 | 3 | Apr, Smr, Spr |
pIE522 | Klebsiella pneumoniae (1996) (35) | ∼38,000 | 42 | ∼1b | Gmr, Kmr, Sur, Tobr | |
pSa | Shigella sp. (1968) (82) | ∼39,000 | 47 | ∼1b | Cmr, Gmr, Kmr, Smr, Spr, Sur |
Tpr, resistance to trimethoprim (20 μg/ml); Sur, resistance to sulfonamide (10 μg/ml); Tcr, resistance to tetracycline (10 μg/ml); Smr, resistance to streptomycin (20 μg/ml); Apr, resistance to ampicillin (100 μg/ml); Spr, resistance to spectinomycin (100 μg/ml); Gmr, resistance to gentamicin (10 μg/ml); Kmr, resistance to kanamycin (50 μg/ml); Cmr, resistance to chloramphenicol (25 μg/ml); Tobr, resistance to tobramycin (10 μg/ml).
Since these plasmids have not been completely sequenced, it is possible (but not likely according to the array results and calculated overall size of the plasmids) that they contain additional indels.