FIG. 2.
Footpad swelling in BALB/c mice immunized s.c. three times in 3-week intervals with Lip-rLmSTI1-CpG ODN, Lip-rLmSTI1, rLmSTI1 plus CpG ODN in PBS, rLmSTI1 plus non-CpG ODN in PBS, empty liposomes, or PBS after challenge with L. major promastigotes. Three weeks after the last booster, the mice (n = 7) were challenged in the left footpad with 1.5 × 106 L. major promastigotes. The footpad thicknesses of mice were measured for both footpads for 14 weeks. Each point represents the average increase in footpad thickness ± standard error of the mean.