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Nucleotide variations (A) and amino acid sequence alignments (B) in esxB and esxA CDSs and their gene products (CFP-10 and ESAT-6, respectively). Position 1 of the nucleotide alignment reflects the start of the gene esxB. For the DNA sequences, only differing nucleotides are shown (positions as indicated). For whole-sequence alignments, see the supplemental material. Orthologous sequences of M. tuberculosis H37Rv and M. bovis AF2122/97 are included in the amino acid alignments.
