Figure 5. An active form of Sd induces tissue overgrowth and activates Hpo target genes.
(A–D) Wild type eye (A), or eyes expressing Sd-GA (B, C) or Sd (D) with GMR-Gal4. (E, F) Adult eyes expressing dMSTn (E) or dMSTn plus Sd-GA (F) with GMR-Gal4. (G-J). Wild type eye discs (G, I) or eye discs expressing Sd-GA with GMR-Gal4 (H, J) were immunostained to show the expression of CycE (G–H) or Diap1 (I–J). (K, K′) A wing disc expressing Sd-GA with hh-Gal4 was immunostained to show the expression of ex-lacZ (blue) and Ci (red). Ci marked the A-compartment.