Table 1.

listing of physical parameters used for numerical simulation

		Hypodermis	Dermis
Optical coefficients [17-20]	μa (mm-1)	0.1	0.04
	μs (mm-1)	9	17
	μ's (mm-1)	0.81	1.53
	g native	0.91	0.91
	μeff (mm-1)	0.52	0.43
	D (mm)	0.36	0.21
Thermal coefficients [21-23]	C (J.g-1.K-1)	2.87	3.3
	ρ (g.mm-3)	0.86.10-3	1.2.10-3
	k (W.mm-1.K-1)	3.02.10-4	4.4.10-4
	wb (ml.100 g-1.min-1)	21	-
	wb (g.mm-3.s-1)	3.5.10-6	-
	h (W.m-2.K-1)	-	15
Tissue Damage Coefficients [11]
	Ea (J.mol-1)	6.28.105	6.28.105
	A (s-1)	3.1.1098	3.1.1098

- μ_a (mm^-1): absorption coefficient in tissue,

- μ_s (mm^-1): scattering coefficient

- μ'_s (mm^-1): reduced scattering coefficient: ${\mu }_s^{\text{'}}={\mu }_s(1-g)$

- g: anisotropy factor μ_eff (mm^-1):

- μ_eff effective attenuation coefficient,

- D (mm): optical diffusion distance

- C: specific heat of tissue (J.g^-1.°K^-1)

- ρ: density of tissue (g mm^-3)

- k: thermal conductivity of tissue (W. mm^-1.°K^-1)

- wb: blood flow rate (ml.100 g^-1.min^-1)

- h heat-transfer coefficient (W.m^-2.K^-1)

- E_a (J.mole^-1): activation energy

- A (s^-1): frequency factor