Table 7.

Survival in trials comparing gemcitabine to gemcitabine plus fluoropyrimidine

Reference	Year	Treatment regimen	Median survival (mo)	p	HR	95% CI
Berlin	2002	Gemcitabine	5.4	0.09	0.82	0.65 – 1.03
		Gemcitabine + 5-FU (bolus)	6.7
Riess	2005	Gemcitabine	6.2	0.68	1.04	0.86 – 1.25
		Gemcitabine + 5-FU (infusional)	5.9
DiCostanzo	2005	Gemcitabine	7.8	--	na	na
		Gemcitabine + 5-FU (CI)	7.5
Scheithauer	2003	Gemcitabine	8.2	--	0.82	0.50 – 1.35
		Gemcitabine + Capecitabine	9.5
Herrmann	2005	Gemcitabine	7.3	0.314	0.89	0.70 – 1.12
		Gemcitabine + Capecitabine	8.4
Cunningham	2005	Gemcitabine	6.0	0.026	0.79	0.65 – 0.97
		Gemcitabine + Capecitabine	7.4

5-FU: 5-fluorouracil; CI = continuous infusion; na = data not available;