TABLE 1.

SUMMARY OF THE CLINICAL CHARACTERISTICS OF SUBJECTS AND PATIENTS

	Nonsmokers	Smokers	COPD
Number	10	10	17
M:F ratio	6:4	8:2	9:8
Age, yr	59 ± 15	58 ± 4	60 ± 7
Smoking, pack-years	0	34 ± 18*	42 ± 19*
FEV1% predicted	98 ± 4	97 ± 13	39 ± 27†
FEV1/FVC, %	81 ± 3	81 ± 2	51 ± 23‡
DlCO, % predicted	80 ± 12	90 ± 10	54 ± 23‡
DlCO/Va, % predicted	86 ± 14	103 ± 13	70 ± 24

Definition of abbreviations: COPD = chronic obstructive pulmonary disease; Dl_CO = diffusing capacity of lung for carbon monoxide; M:F = male:female.

Data shown represents mean ± SEM unless otherwise indicated.

^*P < 0.001 compared with nonsmokers.

^†P < 0.001 compared with nonsmokers and smokers without COPD.

^‡P < 0.05 compared with nonsmokers and smokers without COPD.