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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Dev Cell. 2008 Feb;14(2):275–286. doi: 10.1016/j.devcel.2007.12.005

Figure 7. Model for non-autonomous control of sexual dimorphism in the Drosophila gonad.

Figure 7

Diagram of a male gonad. Anterior is to the left. Sexual dimorphism of three cell types is controlled non-autonomously via different types of male-specific cell-cell signaling from the SGPs: Wnt2 expression induces PC precursor formation, the JAK/STAT pathway regulates male germ cell development, and an unknown signal promotes msSGP survival in male gonads. Inset shows a model for PC specification, in which Wnt2 is regulated by dsx to induce male PC fate in surrounding fat body cells. Although Wnt2 is genetically downstream of dsx as indicated, our data indicate that dsx acts in the female gonad to directly or indirectly repress Wnt2 expression.