TABLE 5.
Predicted gene products of the A. salmonicida subsp. salmonicida MSHA-type cluster based on similarity to the V. cholerae MSHA system
| A. salmonicida subsp. salmonicida gene product | Homologue in V. cholerae | % Amino acid identity | Predicted function, location, and/or Gsp homologue |
|---|---|---|---|
| MshI | MshI | 25 | Inner membrane, GspL |
| MshJ | MshJ | 35 | Inner membrane, GspM |
| MshK | MshK | 33 | Periplasm, unknown function |
| MshL | MshL | 49 | Outer membrane, secretin |
| MshM | MshM | 50 | Cytoplasm, ATPase, GspA |
| MshN/D | MshN N terminus and MshD C terminus | Fusion created by deletion | |
| Partially deleted | MshN | Outer membrane, tetratricopeptide repeat lipoprotein | |
| Absent | MshE | Cytoplasm, traffic ATPase, GspE | |
| Absent | MshG | Inner membrane, GspF | |
| Absent | MshF | Unknown function | |
| Absent | MshB | Pseudopilin | |
| Absent | MshA | Pilin subunit | |
| Absent | MshC | Pseudopilin | |
| Partially deleted | MshD | Pseudopilin | |
| MshO | MshO | 31 | Pseudopilin |
| MshP | MshP | 24 | Pseudopilin |
| MshQ | MshQ | 39 | Outer membrane, similar to PilY1 |