FIG. 2.

Representative clinical pictures and histology. C57BL/6J mice received intravitreal injections of either sterile saline or 500 CFU or 5,000 CFU S. aureus. At 24, 48, 72, and 96 h, the eyes were photographed and then removed, sectioned, and stained for HE. Mild inflammation was observed in eyes that received 500 CFU, and severe retinal damage was observed in eyes that received 5,000 CFU. Retinal detachment in saline- and 500-CFU-injected eyes is an artifact of tissue sectioning. HE pictures were taken of whole eyes at ×2 magnification, and the retina at ×20 magnification. C, cornea; L, lens; R, retina; V, vitreous; IP, inner plexiform; INL, inner nuclear layer; ONL, outer nuclear layer.