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. 2008 Jan 28;76(4):1781–1790. doi: 10.1128/IAI.01285-07

FIG. 4.

FIG. 4.

Expression of αB-crystallin and active caspase 3. C57BL/6J mice received intravitreal injections of sterile saline or 500 CFU or 5,000 CFU S. aureus. (A) Representative Western blot results probing for αB-crystallin (22 kDa) and actin (43 kDa) loading control. Two samples per group per time point are shown. (B) Densitometry of Western blot results, probing for αB-crystallin. The data are shown as the mean [(αB-crystallin/actin) injected sample]/[(αB-crystallin/actin) normal control]. Saline, n = 3; 500 CFU, n = 4; 5,000 CFU, n ≥ 5. Standard error of the mean: *, P < 0.05 for 5,000 versus saline or 500 CFU full αB-crystallin. (C) Representative Western blot results using an active caspase 3-specific antibody in eyes that received 5,000 CFU S. aureus. (D) Percentages of eyes by Western blot analysis expressing active caspase 3 at 24, 48, 72, and 96 h in C57BL/6J mice following sterile-saline or 500- or 5,000-CFU S. aureus injection. Saline, n = 3; 500 CFU, n = 4; 5,000 CFU, n ≥ 5.

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