TABLE 1.
Technique and no. of loci | No. of different profiles | No. of isolates with unique profiles | No. of clusters | No. of isolates in cluster | Strain-clustering rate (%) |
---|---|---|---|---|---|
Spoligotyping | 113 | 76 | 37 | 182 | 56.2 |
IS6110-RFLP | 195 | 167 | 28 | 91 | 24.4 |
Low copy no. (≤5 IS6110 bands [n = 28]) | 12 | 7 | 5 | 21 | 57.1 |
High copy no. (<5 IS6110 bands [n = 230]) | 183 | 160 | 23 | 70 | 20.4 |
IS6110-RFLP and spoligotyping | 206 | 180 | 26 | 78 | 20.2 |
15 MIRU-VNTR loci | 207 | 180 | 27 | 78 | 19.8 |
Spoligotyping and 15 MIRU-VNTR loci | 207 | 180 | 27 | 78 | 19.8 |
IS6110-RFLP and 15 MIRU-VNTR loci | 213 | 189 | 24 | 69 | 17.4 |
IS6110-RFLP, spoligotyping, and 15 MIRU-VNTR loci | 213 | 189 | 24 | 69 | 17.4 |
The techniques referred to as 15 and 24 MIRU-VNTR loci correspond to the optimized formats defined in reference 37.