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. 2008 Jan 30;46(4):1398–1406. doi: 10.1128/JCM.02089-07

TABLE 1.

Discriminatory power and cluster identification in a test panel (77% of all genotyped isolates from Brussels during a 16-month period; n = 258)a

Technique and no. of loci No. of different profiles No. of isolates with unique profiles No. of clusters No. of isolates in cluster Strain-clustering rate (%)
Spoligotyping 113 76 37 182 56.2
IS6110-RFLP 195 167 28 91 24.4
    Low copy no. (≤5 IS6110 bands [n = 28]) 12 7 5 21 57.1
    High copy no. (<5 IS6110 bands [n = 230]) 183 160 23 70 20.4
IS6110-RFLP and spoligotyping 206 180 26 78 20.2
15 MIRU-VNTR loci 207 180 27 78 19.8
Spoligotyping and 15 MIRU-VNTR loci 207 180 27 78 19.8
IS6110-RFLP and 15 MIRU-VNTR loci 213 189 24 69 17.4
IS6110-RFLP, spoligotyping, and 15 MIRU-VNTR loci 213 189 24 69 17.4
a

The techniques referred to as 15 and 24 MIRU-VNTR loci correspond to the optimized formats defined in reference 37.